Not an obvious sport that you would associate with foot blisters but yes, cyclists, although they are technically, a non-weight-bearing sport, do get affected by blisters!
Cycling shoes should definitely be tried on at a shop to get a great fit, branding is irrelevant, they should just work for you, internet purchasing for this type (or any other type really) of footwear, can lead to incorrect fitting to the foot. From a Podiatrists perspective the shoe should be neutral as any biomechanical issues can be resolved by prescription orthotics.
The foot in a cycling shoe is kept at the midstance part of the gait cycle and because of that, it is quite unstable but in cycling the foot need to be more stable and a rigid lever, which could easily be addressed by orthotics. This instability causes movement within the cycling shoe, and too much movement of the foot in the shoe, causes friction, which then can cause blisters. Podiatrist are really good at prescribing this type of orthotics and gait and motion clinics have the pressure gait analysis to mimic cycling pressures on the foot.
My youngest son, who road bikes, informs me `heel blisters are by far the worst ones `. These blisters are caused, when the cyclist gets out of the seat and rides uphill, the heel starts to move in the back of the shoe, causing heel blisters.
Making sure the shoe is a snug fit but not too tight and that the feet are retained in the shoe are important factors that will reduce the movement of the foot at the back of the shoe preventing the friction that causes heel blisters.
Moisture Wicking socks
Such as Darn Tough are the best for cycling as the feet still sweat and create moisture next to the skin, make sure there is room in the cycling shoe and thinner socks would work better here.
Armaskin liner socks
Armaskin liner socks would work really well here for all locations of blisters on the foot, they won’t work by themselves as they need an outer sock as well.
Engo patches placed in the areas of the shoe that are creating hotspots would reduce any friction caused by the shoe. These are so slim; they will fit in any shoe and not take up any room.
Taping the skin with Hypafix and KT Pro tapes
Hypafix and KT Pro tapes are great blister prevention measures along with 2toms blister powder applied on the top of the taping
2 Toms Blister Powder / 2Toms Blistershield
2Toms products are both friction reducing products, one is powder and the other a liquid. They can be applied to the skin as a blister prevention product, do not apply to broken skin not empty into a sock.
Epitact gel ovals and the gel heel sleeves
are reusable products to prevent blisters, they are applied to the skin and are thin enough to not cause any added pressure.
It’s just finding what works for you on an individual basis! If you already have a blister, then treat it with dressings that are appropriate to which stage the blister is in. All found in Blisterhelp’s Emergency Blister kit and the Blister prevention and treatment kit.